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Fillers research

Filler papers treat eyelid and periorbital hollowing with hyaluronic acid and other injectable fillers.

128
Papers
78
Since 2021
1
Reviews and meta-analyses
2005
First paper

Papers, newest first

2026
The Blending Technique: A New Approach for Tear Trough Correction
Beut J, Guisantes E, Jelks GW, Jelks EB, Wong CH · Aesthetic Plast Surg · PMID 42443423
2026
Association of AbobotulinumtoxinA and Skinbooster for Periorbital Wrinkles: A Randomized, Controlled, Double-Blind, Split-Face Study
Shishido ACLN, Tostes LLL, de Souza Nobre BB, Gonçalves JR, de Sousa Mendes LA, Carbone AC, et al. · Aesthetic Plast Surg · PMID 42420660
2026
Hybrid Biostimulator and Hyaluronic Acid Injectable for Tear Trough Rejuvenation
Young SM, Lau EKH · Aesthetic Plast Surg · PMID 42098500
2026
Hyaluronic Acid Fillers Versus Polynucleotides for Under-Eye Rejuvenation
Khan RS, Hafeez K · J Clin Med · PMID 42452433
2026
Modifying Upper Eyelid Crease Using Hyaluronic Acid Fillers: A Clinical Case Series
Kim E, Namkoong W, Lee S, Yi KH · J Craniofac Surg · PMID 42138323
2026
Injectable Platelet-Rich Fibrin for Blepharoplasty: Healing and Postoperative Outcomes
Isgandarova S, Aliyev T, Mammadov J, Hasanov F · Aesthet Surg J · PMID 41735797
2026
Late-Onset Upper Eyelid Edema Following Temporal Hollow Correction With Hyaluronic Acid
El Feghaly C, Tawa P · Plast Reconstr Surg Glob Open · PMID 41959944
2026
Hyaluronic acid fillers for supraorbital hollowing: A prospective cohort study of efficacy and longevity
Yi KH, Koppert E, Fai WK, Wan J · J Plast Reconstr Aesthet Surg · PMID 41850033
2026
Current Approaches in Periocular Rejuvenation: Our 6-year Experience
Lustig-Barzelay Y, Landau-Prat D, Ben-Simon GJ · Aesthetic Plast Surg · PMID 41663769
2026
Single-Session High-Dose Hyaluronidase for Managing Periorbital Hyaluronic Acid Filler Complications
Chen J, Zhang F, Li C, Wang Y, Li Q, Weng X, et al. · Aesthetic Plast Surg · PMID 41145865
2026
Hyaluronic Acid vs Poly-L-Lactic Acid for the Treatment of Upper-Eyelid Hollowing: A Prospective Cohort Study
Zheng B, Sun S, Liu S, Gao J, Zhao R, Zhang J, et al. · Aesthet Surg J Open Forum · PMID 41799414
2025
Navigating Lower Eyelid Blepharoplasty in Patients with Under-Eye Filler: Challenges, Complications, and Recommendations
Yao A, Shah-Desai S, Malhotra R, Patel B · Plast Reconstr Surg · PMID 41358743
2025
Long-Term Effects of Tear Trough Hyaluronic Acid Filler: A Retrospective Study
Puyana C, Montes JR · J Clin Aesthet Dermatol · PMID 41446717
2025
Iatrogenic migration from a multiple filler injections for tear trough: A case report
Zhang W, Pan Y · Int J Surg Case Rep · PMID 40972126
2025
Application of Orbital Septal Fat Repositioning Combined With SVF-Gel Fillers in Lower Blepharoplasty
Zhang H, Zhang Y, Lu Z, Qian J, Ye Z, Long X · J Craniofac Surg · PMID 40146291
2025
Application of High-frequency Ultrasound for Detection and Characterization of Dermal Fillers in the Periorbital Region
Zhang Z, Jia Y, Tawulan T, Zhuang J, Su X, Chai H, et al. · Plast Reconstr Surg Glob Open · PMID 40881251
2025
Assessing the Informational Value of Large Language Models Responses in Aesthetic Surgery: A Comparative Analysis with Expert Opinions
Grippaudo FR, Jeri M, Pezzella M, Orlando M, Ribuffo D · Aesthetic Plast Surg · PMID 39966152
2025
Role of Hyaluronic Acid in Post-Blepharoplasty Volume Restoration and Complication Management: A Systematic Review
Safia A, Abd Elhadi U, Merchavy S, Batheesh R, Bathish N · J Clin Med · PMID 40648944
2025
Response to: Correction of Tear Trough Deformity with Minced Orbital Fat Grafts During Transconjunctival Lower Blepharoplasty
Mohammadbeigy I, Pourazizi M, Eshraghi B · Aesthetic Plast Surg · PMID 39313662
2025
Quantitative Assessment of New Frontiers in Dermatochalasis and Periorbital Hyperpigmentation Treatment: The Role of Cross-Linked Porcine Collagen
Chuang AD, Lin ET, Wu BQ, Lu ME, Chiang HM, Chu PN, et al. · Aesthetic Plast Surg · PMID 39407005
2025
In Vitro Evaluation and Clinical Effects of a Regenerative Complex with Non-Cross-Linked Hyaluronic Acid and a High-Molecular-Weight Polynucleotide for Periorbital Treatment
Abuyousif HS, Porcello A, Cerrano M, Marques C, Scaletta C, Lourenço K, et al. · Polymers (Basel) · PMID 40076130
2025
Anatomy-Based Filler Injection: Treatment Techniques for Supraorbital Hollowness and Charming Roll
Hong GW, Choi W, Wan J, Yoon SE, Bautzer C, Basmage L, et al. · Life (Basel) · PMID 40003713
2025
[Modern spacers for the correction of lower eyelid retraction]
Sheptulin VA, Grusha YO · Vestn Oftalmol · PMID 41432515
2025
Antiaging Strategies Utilizing Multilayer Rejuvenation
Choi W, Wan J, Yi KH · Plast Aesthet Nurs (Phila) · PMID 41026732
2024
Late-onset periorbital edema in patients with a history of facial hyaluronic acid injection: A review on diagnosis and management
Eshraghi B, Babaei L, Aghajani M, Aghajani A · J Plast Reconstr Aesthet Surg · PMID 39395232
2024
Surgical and Non-Surgical Approach for Tear Trough Correction: Fat Repositioning Versus Hyaluronic Acid Fillers
Christodoulou S, Tzamalis A, Tsinopoulos I, Ziakas N · J Pers Med · PMID 39590588
2024
Correction of Infraorbital Dark Circles Using Autologous Adipose-Derived Collagen Filler: A Novel Regenerative Option
Cheong S, Yang H, Hao C, Lu F, He Y · Aesthetic Plast Surg · PMID 39390124
2024
Static and Dynamic Filler-Associated Tear Trough Deformities: Manifestations and Treatment Algorithm
Kang Y, Wang S, Xia Z, Zhang X, Yu N, Liu Z, et al. · Aesthetic Plast Surg · PMID 38727846
2024
Fat or fillers: The dilemma in eyelid surgery
Miotti G, De Marco L, Quaglia D, Grando M, Salati C, Spadea L, et al. · World J Clin Cases · PMID 38898854
2024
A novel hybrid BonT-A and hyaluronic acid cannula-based technique for eyelid ptosis and periorbital rejuvenation
Hernández LAP, Hernández AMP, Castelanich D, Shitara D, Chacín M · J Cosmet Dermatol · PMID 38514912
2024
Applied Anatomy of the Lower Eyelid Preseptal Space for Treating Ectropion and Retraction with Soft-Tissue Fillers
Hartstein ME, Gildener-Leapman J, Bernardini FP, Cassuto D, Wulc AE, Ni G, et al. · Plast Reconstr Surg · PMID 37285216
2024
Periorbital Rejuvenation
Barbee PH · Atlas Oral Maxillofac Surg Clin North Am · PMID 38307635
2024
The Efficacy and Safety of Hyaluronic Acid Injection in Tear Trough Deformity: A Systematic Review and Meta-analysis
Liu X, Gao Y, Ma J, Li J · Aesthetic Plast Surg · Meta-Analysis · PMID 37684413
2024
Nonsurgical management of upper eyelid retraction in thyroid eye disease
Young SM, Kim YD, Woo KI · Taiwan J Ophthalmol · PMID 39803393
2023
Hyaluronic acid gel injection for dysthyroid upper eyelid retraction in Asian patients
Young SM, Kim JH, Kim YD, Karnsiritanont V, Lang SS, Woo KI · Orbit · PMID 36082627
2023
Ophthalmic Complications of Periorbital and Facial Aesthetic Procedures: A Literature Review
Alharbi MM, Bin Dlaim MS, Alqahtani JM, Alkhudhairy NS, Almasoudi SM, Alajmi NT · Cureus · PMID 37529817
2023
Infraorbital mass long after dermal filler injection: A report of two cases
Arici C, Tosuner Z · J Cosmet Dermatol · PMID 36606376
2023
Modern blepharoplasty: From bench to bedside
Miotti G, Zeppieri M, Pederzani G, Salati C, Parodi PC · World J Clin Cases · PMID 36969996
2023
Adjunctive Aesthetic Procedures in Orthognathic Surgery
Jansma J, Schepers RH · Oral Maxillofac Surg Clin North Am · PMID 36336602
2023
Infraorbital Hollow Rejuvenation: Considerations, Complications, and the Contributions of Midface Volumization
Woodward J, Cox SE, Kato K, Urdiales-Galvez F, Boyd C, Ashourian N · Aesthet Surg J Open Forum · PMID 36998744
2022
Does hyaluronidase injected in periocular area change skin ultrastructure?: Standardized in vitro analysis
Aguilar-González M, Davó-Cabrera J, Rausell-Fontestad N, Botella-Estrada R, España-Gregori E, Pérez-López M · J Cosmet Dermatol · PMID 35451166
2022
Why Devote an Entire Issue to Injectables?
Nahai F · Aesthet Surg J · PMID 36102829
2022
2022
Use of Cosmetic Facial Injectables After Facial Aesthetic Surgery
Talwar AA, Shulkin JM, Hitchner M, McAuliffe PB, Desai AA, Broach RB, et al. · Aesthet Surg J · PMID 35764098
2022
Delayed complication of botulinum toxin and hyaluronic acid filler injections: A case report
Lai D, Liu H, Kong L, Cheng S · J Cosmet Dermatol · PMID 35460324
2022
Aesthetic Enhancement of the Brow using Hydroxyapatite
Minelli L, Richa J, Mendelson BC · Aesthetic Plast Surg · PMID 35288761
2022
Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double-blind, split-face trial
Lee YJ, Kim HT, Lee YJ, Paik SH, Moon YS, Lee WJ, et al. · J Dermatolog Treat · Randomized Controlled Trial · PMID 32248707
2022
Detection of the Safe Zone for Upper Eyelid Hyaluronic Acid Injections
Can B, BetülGözel · Indian J Dermatol · PMID 36092216
2021
Platelet-Rich Plasma in Aesthetics
Nanda S, Chauhan K, Shetty V, Dashore S, Bhatia S · Indian Dermatol Online J · PMID 34976880
2021
Xanthelasma palpebrarum after hyaluronic acid injection in the lower eyelid: A case report and review of the literature
Simões Pires V, Wender IO, Santos MF, Sartori GL, Vivian A, Dallagnese G · J Cosmet Dermatol · PMID 33387399
2021
New era in upper eyelid rejuvenation: A brief overview of non-surgical blepharoplasty techniques
Theodorelou-Charitou SA, Xanthos T, Nikas IP, Ntinioti T · J Plast Reconstr Aesthet Surg · PMID 33602571
2021
2021
Eyelid and Periorbital Dermal Fillers: Products, Techniques, and Outcomes
Montes JR, Santos E, Amaral C · Facial Plast Surg Clin North Am · PMID 33906765
2021
Late-Onset Upper Eyelid and Brow Edema as a Long-Term Complication of Hyaluronic Acid Filler Injection
Dubinsky-Pertzov B, Bernardini FP, Or L, Gazit I, Hartstein ME · Aesthet Surg J · PMID 32427315
2021
Upper eyelid blepharoplasty following hyaluronic acid injection with improved facial aesthetics and eye symptoms: a case report
Maione L, Vinci V, Costanzo D, Battistini A, Lisa A, Di Maria A · J Med Case Rep · PMID 33926525
2021
Management of Tear Trough with Hyaluronic Acid Fillers: A Clinical-Practice Dual Approach
Urdiales-Gálvez F, Farollch-Prats L · Clin Cosmet Investig Dermatol · PMID 34012281
2020
Anatomical and ultrasound-based injections for sunken upper eyelid correction
Tansatit T, Phumyoo T, Jitaree B, Sahraoui YME, Lee JH · J Cosmet Dermatol · PMID 31222959
2020
Rehabilitation of the Dysmorphic Lower Eyelid From Hyaluronic Acid Filler: What to Do After a Good Periocular Treatment Goes Bad
Skippen B, Baldelli I, Hartstein M, Casabona G, Montes JR, Bernardini F · Aesthet Surg J · PMID 30877762
2020
Comparison between hyaluronic acid filler and botulinum toxin type A in the treatment of thyroid upper eyelid retraction
Hassan Hussien M, Abd El-Wahed Hassan E, El-Haddad NSEM · Ther Adv Ophthalmol · PMID 33447731
2019
Reporting outcomes of hyaluronic gel filler as a treatment for epiblepharon
Bladen JC, Malhotra R · Graefes Arch Clin Exp Ophthalmol · PMID 31641882
2019
The Injection for the Lower Eyelid Retraction: A Mechanical Analysis of the Lifting Effect of the Hyaluronic Acid
Xi W, Han S, Feng S, Li K, Brunetti B, Lazzeri D, et al. · Aesthetic Plast Surg · PMID 31399822
2019
Surgical Cosmetic Procedures of the Face
Devgan L, Singh P, Durairaj K · Otolaryngol Clin North Am · PMID 30954269
2019
Correction of Tear Trough Deformity Using Autologous Fibroblast Combined with Keratin: New Soft Tissue Filler
Xing W, Zhang C, Zhang J, Zhang Q · Aesthetic Plast Surg · PMID 30456637
2019
Managing Periocular Filler-Related Syndrome Prior to Lower Blepharoplasty
Zoumalan CI · Aesthetic Plast Surg · PMID 30298348
2019
Non-surgical treatment of lower eyelid fat pads with an injectable solution acid deoxycholic based
Amore R, Sbarbati A, Amuso D, Leonardi V, Alsanafi S, Greco Lucchina A, et al. · J Biol Regul Homeost Agents · PMID 32425031
2019
The case of the eyelid silicone granulomas
Wulu JA, Garcia-Rodriguez L, Prilutskiy A, Spiegel JH · Am J Otolaryngol · PMID 31133360
2018
Non-aesthetic indications for periocular hyaluronic acid filler treatment: a review
Tan P, Kwong TQ, Malhotra R · Br J Ophthalmol · PMID 29146758
2018
Rejuvenation of the Upper Face and Brow: Neuromodulators and Fillers
Lighthall JG · Facial Plast Surg · PMID 29631280
2018
Volumization of the Brow at the Time of Blepharoplasty: Treating the Eyebrow Fat Pad as an Independent Unit
Vrcek I, Chou E, Somogyi M, Shore JW · Ophthalmic Plast Reconstr Surg · PMID 28369020
2017
2017
The Role of Injectables in Aesthetic Surgery: Financial Implications
Richards BG, Schleicher WF, D'Souza GF, Isakov R, Zins JE · Aesthet Surg J · PMID 29025237
2017
Xanthelasma-Like Reaction to Filler Injection
Or L, Eviatar JA, Massry GG, Bernardini FP, Hartstein ME · Ophthalmic Plast Reconstr Surg · PMID 27218809
2016
Tear trough deformity: different types of anatomy and treatment options
Jiang J, Wang X, Chen R, Xia X, Sun S, Hu K · Postepy Dermatol Alergol · PMID 27605904
2016
Upper Eyelid Filling With or Without Surgical Treatment
Romeo F · Aesthetic Plast Surg · PMID 26893281
2016
Overview of Facial Plastic Surgery and Current Developments
Chuang J, Barnes C, Wong BJF · Surg J (N Y) · PMID 28824978
2016
Periorbital Injectables: Understanding and Avoiding Complications
Hwang CJ · J Cutan Aesthet Surg · PMID 27398006
2016
Upper eyelid granuloma: a rare delayed-onset complication secondary to cosmetic filler injection on forehead
Pao SI, Lin SM, Chang YH, Chiang SY · Int Med Case Rep J · PMID 27382336
2015
Retained Dermal Filler in the Upper Eyelid Masquerading as Periorbital Edema
Khan TT, Woodward JA · Dermatol Surg · PMID 26317905
2015
Comprehensive Treatment of Periorbital Region with Hyaluronic Acid
Bravo BS, Rocha CR, Bastos JT, Silva PM · J Clin Aesthet Dermatol · PMID 26155325
2015
Minimally invasive options for the brow and upper lid
Briceño CA, Zhang-Nunes SX, Massry GG · Facial Plast Surg Clin North Am · PMID 25921566
2015
Filler Migration: A Number of Mechanisms to Consider
Jordan DR, Stoica B · Ophthalmic Plast Reconstr Surg · PMID 25650796
2015
Injectable 5-FU with or without added steroid in periorbital skin grafting: initial observations
Yoo DB, Azizzadeh B, Massry GG · Ophthalmic Plast Reconstr Surg · PMID 25025385
2014
[Cosmetic eyelid surgery]
Ruban JM, Barbier J, Malet T, Baggio E · J Fr Ophtalmol · PMID 24275517
2014
Hyaluronic acid gel injection for upper eyelid retraction in thyroid eye disease: functional and dynamic high-resolution ultrasound evaluation
Kohn JC, Rootman DB, Liu W, Goh AS, Hwang CJ, Goldberg RA · Ophthalmic Plast Reconstr Surg · PMID 24833450
2013
Novel use of polymethyl methacrylate (PMMA) microspheres in the treatment of infraorbital rhytids
Mani N, McLeod J, Sauder MB, Sauder DN, Bothwell MR · J Cosmet Dermatol · PMID 24305426
2013
Injectable hyaluronic acid fillers for periorbital rejuvenation
Lee S, Yen MT · Int Ophthalmol Clin · PMID 23751427
2012
Correction of tear troughs and periorbital lines with a range of customized hyaluronic acid fillers
Rzany B, Cartier H, Kestermont P, Trevidic P, Sattler G, Kerrouche N, et al. · J Drugs Dermatol · PMID 22497041
2011
Modifying the upper eyelid crease in Asian patients with hyaluronic acid fillers
Choi HS, Whipple KM, Oh SR, Priel A, Looi A, Korn BS, et al. · Plast Reconstr Surg · PMID 21285787
2011
Hyaluronic acid treatment for upper eyelid retraction after glaucoma filtering surgery
Vásquez LM, González-Candial M · Orbit · PMID 21281072
2011
Nonsurgical management of upper eyelid margin asymmetry using hyaluronic acid gel filler
Mancini R, Khadavi NM, Goldberg RA · Ophthalmic Plast Reconstr Surg · PMID 20551854
2011
Use of hyaluronic acid filler for tear-trough rejuvenation as an alternative to lower eyelid surgery
Morley AM, Malhotra R · Ophthalmic Plast Reconstr Surg · PMID 20551859
2009
Perspectives in the selection of hyaluronic acid fillers for facial wrinkles and aging skin
John HE, Price RD · Patient Prefer Adherence · PMID 19936165
2009
Blindness after facial contour augmentation with injectable silicone
Tangsirichaipong A · J Med Assoc Thai · PMID 19702074
2009
Use of hyaluronic Acid gel for upper eyelid filling and contouring
Morley AM, Taban M, Malhotra R, Goldberg RA · Ophthalmic Plast Reconstr Surg · PMID 19935245
2008
The scientific basis for lipotransfer: is it the ideal filler?
Jatana KR, Smith SP · Facial Plast Surg Clin North Am · PMID 19056057
2008
Osteoplasty using calcium hydroxylapatite filler
Vagefi MR, McMullan TF, McCann JD, Anderson RL · Ophthalmic Plast Reconstr Surg · PMID 18520833
2007
Evaluation and treatment of the tear trough deformity in lower blepharoplasty
Espinoza GM, Holds JB · Semin Plast Surg · PMID 20567659
2007
Fillers in the periorbital complex
Finn JC, Cox S · Facial Plast Surg Clin North Am · PMID 17317563
2006
Hyaluronic acid gel (Restylane) filler for facial rhytids: lessons learned from American Society of Ophthalmic Plastic and Reconstructive Surgery member treatment of 286 patients
McCracken MS, Khan JA, Wulc AE, Holds JB, Fante RG, Migliori ME, et al. · Ophthalmic Plast Reconstr Surg · PMID 16714927