Origins of the term, 1818-1907
- Karl Ferdinand von Graefe, a Berlin surgeon, introduced "Blepharoplastik" into the medical literature in 1818, for a case of eyelid reconstruction he had performed in 1809 (non-PubMed; corroborating: non-PubMed).
- Sichel published the first detailed description of herniated orbital fat in 1844; it did not lead to a wave of surgery because surgery at that time was performed only for functional reasons, and Sichel credited the earlier work of Dupuytren (non-PubMed).
- Charles Conrad Miller published the first photograph showing resection of excess lower-eyelid skin in the early 1900s, in an approach similar to techniques used today; in 1907 he produced the first published book on cosmetic surgery, "Cosmetic Surgery: The Correction of Featural Imperfections" (PMID 21319687; non-PubMed).
- In Japan, M. Mikamo reported the first cases of a double-eyelid operation for aesthetic purposes in 1896, at a time of social transition and early Westernization; a first English translation of his original article was published in 1997 (PMID 9047184).
Technique milestones, 1924-2004
- Julien Bourguet of France first described a transconjunctival approach to resecting herniated periorbital fat in 1924 (PMID 21319687; non-PubMed).
- Salvador Castañares codified "subtractive" blepharoplasty, skin, muscle and fat excision on an anatomical basis, in 1951, after describing the fat compartments of the upper and lower orbit (PMID 14864073; PMID 21319687; non-PubMed).
- Fasanella and Servat published "levator resection for minimal ptosis" in 1961, a simplified tarsoconjunctival-Müller muscle resection for small amounts of ptosis, still performed as the Fasanella-Servat procedure (PMID 13698293).
- Jones, Quickert and Wobig described aponeurotic repair for involutional ptosis in 1975: 57 eyelids in 34 patients with 8 mm or more of levator excursion, operated through a skin incision, with excellent results and minimal trauma (PMID 1156224).
- In the same 1975 issue of Archives of Ophthalmology, Putterman and Urist described Müller muscle-conjunctiva resection (MMCR), a posterior-approach technique selected by a positive response to 10% phenylephrine, with satisfactory results in 27 of 28 eyelids (PMID 1156223).
- Loeb described fat-pad "sliding" in 1981: mobilizing vascularized medial and central lower-lid fat through a subciliary incision to fill the tear trough, rather than excising it (PMID 7338007; technique described in PMID 21319687).
- Hamra modified Loeb's technique in 1995 with arcus marginalis release, advancing lower-lid fat over the orbital rim under the repositioned orbicularis muscle in 152 cases over 3 years; he revised this to the "septal reset" technique in 2004 (PMID 7624408, PMID 15253208).
- Goldberg described fat repositioning through a transconjunctival approach in 1998, then a subperiosteal-pocket version of it in 2000, followed in 24 patients for 6 to 30 months with good graft viability and patient acceptance; a related paper on maintaining infraorbital rim contour followed in 1999 (PMID 9787211, PMID 10697189, PMID 11816085).
Results and evidence: how the published record has grown
- Of the 100 most-cited periorbital-rejuvenation articles published from January 1989 to April 2020, 53 came out in the 1989-1999 decade, more than any later decade; mean citations per article were 75 (SD 42); 82 originated in the USA and 81 appeared in plastic surgery journals; plastic surgeons wrote 71 and oculoplastic surgeons 22; of 69 clinical studies, 45 (79%) provided only level IV evidence (PMID 36837432).
- Of the top 100 cosmetic upper-facial articles over 50 years, average citations were 55.1 (SD 38.7); surgical methods were the largest single study area at 30%, followed by botulinum toxin (29%) and complication management (15%); invasive procedures made up 55% of the set, and the late 1990s and 2000s were the period of fastest growth (PMID 39867419).
- A 20-year Web of Science analysis of blepharoplasty publications (2002-2021) found 1,125 papers, with output rising every year; Aesthetic Plastic Surgery carried the most papers and Plastic and Reconstructive Surgery was cited most; Massry GG was the most prolific author and Hamra ST the most co-cited author, and Rohrich RJ had the highest citations per publication (PMID 36203097); a letter responding to this analysis followed in 2024 (PMID 37798496).
- Among the top 50 cited blepharoplasty papers from 2015-2022, citation counts ranged from 9 to 37 and altmetric attention scores from 0 to 54; output and citations both peaked in 2021, and the most productive institution was the University of California System (PMID 37153349).
- Across five decades (1970s-2010s) of the top 50 cited articles per decade, plastic surgeons held the largest first-authorship share in blepharoplasty at every time point, while ophthalmology's contribution to the blepharoplasty literature grew over that period (PMID 26994394).
Risks and complications: how the safety record changed
- The older skin-muscle-fat technique removed enough tissue to leave some patients with a hollow orbit and a visibly operated look; current methods remove less tissue for that reason (PMID 15536308).
- A 1986 review of roughly 60 published blindness cases after cosmetic blepharoplasty found retrobulbar hemorrhage in most, with the final injury usually retinal or optic-nerve ischemia; this review is still cited as the baseline case series for blepharoplasty-related vision loss (PMID 3516289).
- "Post-upper blepharoplasty syndrome," ptosis, a hollow sulcus and a high crease from an earlier generation of aggressive fat removal, was traced in 48 eyelids to levator aponeurosis disinsertion bound into septal scar; recognizing this pattern shaped how surgeons now handle the septum during fat removal (PMID 31802837).
- Full current complication rates and their evidence appear in upper blepharoplasty and lower blepharoplasty.
Recovery
- The literature carries no direct historical comparison of recovery time across eras of blepharoplasty technique.
- Holds's own current lower-lid technique, combining septal reset with a transconjunctival incision, is described as an in-office procedure using a CO2 laser, a shift from the hospital-based skin-incision surgery of the mid-twentieth century (PMID 21319687).
- Current recovery evidence, including trials of ice, arnica and bromelain, is in upper blepharoplasty.
Combined procedures
- Ramirez described raising the forehead and brow through the upper-blepharoplasty incision itself in 1996, dissecting to the orbital rim and beyond with endoscopic assistance in 12 of 14 patients, avoiding a separate brow-lift incision (PMID 8988768).
- Codner's 2010 overview of blepharoplasty and brow lift describes upper-lid blepharoplasty combined with supratarsal fixation as a standard pairing (PMID 20595828).
- In the Tracking Operations and Outcomes for Plastic Surgeons database of 13,346 facelift patients, blepharoplasty was the most common procedure added to a facelift (PMID 32459769).
- Current combined-procedure complication data are in upper blepharoplasty, browpexy and direct brow lift, and temporal and lateral brow lift.
Current questions
- Which posterior ptosis technique should be first-line: a 2011 review traced a swing in preference back toward Putterman's 1975 Müller muscle-conjunctiva resection, driven by differing views of what causes involutional ptosis, the predictability of MMCR, and its speed compared with Jones's external levator advancement (PMID 21730839).
- Who is publishing this history now: bibliometric analyses through 2025 disagree about the most-cited and most-prolific authors and institutions in the field, and at least one of these analyses has drawn a published rebuttal (PMID 36203097, PMID 37798496, PMID 39867419).
- How the double-eyelid lineage that began with Mikamo in 1896 is now written: since 1989, the epicanthal-fold surgery literature has been authored predominantly by surgeons of East Asian descent (PMID 38281686).
- Whether quality-of-life outcomes justify techniques descended from the 1975 ptosis papers: a 2025 American Academy of Ophthalmology report reviewed health-related quality-of-life evidence for upper blepharoplasty and blepharoptosis surgery (PMID 40913605).
- Whether mild ptosis, the condition Fasanella and Servat operated on in 1961, is still being missed: a 2021 survey of 214 Aesthetic Society members concluded mild to moderate ptosis remains underrecognized among blepharoplasty patients (PMID 33346340).
- Whether von Graefe's original functional framing of eyelid surgery still fits: a 2026 review argues that visual field testing alone, the standard functional test descended from that framing, misses the full burden of dermatochalasis (PMID 42693598).
Terms
- Blepharoplastik: the 1818 German term for eyelid reconstruction, source of the modern word blepharoplasty (non-PubMed).
- Subtractive blepharoplasty: skin, muscle and fat excision, the technique Castañares codified in 1951 (PMID 21319687).
- Transconjunctival approach: an incision on the inner eyelid surface, avoiding a skin incision, first described by Bourguet in 1924 for fat removal and by Goldberg in 1998 for fat repositioning (PMID 21319687, PMID 9787211).
- Fat repositioning: moving orbital fat over the orbital rim instead of removing it, developed by Loeb, Hamra and Goldberg between 1981 and 2000 (PMID 7338007, PMID 10697189).
- Arcus marginalis: the ligament at the orbital rim that Hamra released in 1995 to advance lower-lid fat (PMID 7624408).
- Aponeurotic ptosis repair: Jones's 1975 technique of re-suturing a dehisced or disinserted levator aponeurosis (PMID 1156224).
- Müller muscle-conjunctiva resection (MMCR): Putterman's 1975 posterior-approach ptosis operation (PMID 1156223).
- Fasanella-Servat procedure: the 1961 tarsoconjunctival-Müller muscle resection for minimal ptosis (PMID 13698293).
- Double-eyelid operation: surgery to create a supratarsal crease in an eyelid without one, first reported for aesthetic purposes by Mikamo in 1896 (PMID 9047184).
- Post-upper blepharoplasty syndrome: ptosis, sulcus hollowing and a high crease from aggressive fat and tissue removal, traced to levator disinsertion in septal scar (PMID 31802837).
Papers
| PMID | First author | Year | Journal | Title | Finding |
|---|---|---|---|---|---|
| 21319687 | Holds JB | 2010 | Mo Med | Lower eyelid blepharoplasty: a procedure in evolution. | Historical review: Miller, Bourguet 1924, Castañares 1951, Loeb 1981, Hamra 1995/2004, Goldberg 1998 |
| 9047184 | Mikamo M | 1997 | Plast Reconstr Surg | Mikamo's double-eyelid operation: the advent of Japanese aesthetic surgery. 1896. | First English translation of the 1896 original double-eyelid paper (landmark) |
| 14864073 | Castanares S | 1951 | Plast Reconstr Surg (1946) | Blepharoplasty for herniated intraorbital fat; anatomical basis for a new approach. | Codified subtractive blepharoplasty on an anatomical basis (landmark) |
| 13698293 | Fasanella RM | 1961 | Arch Ophthalmol | Levator resection for minimal ptosis: another simplified operation. | Origin of the Fasanella-Servat procedure (landmark) |
| 1156224 | Jones LT | 1975 | Arch Ophthalmol | The cure of ptosis by aponeurotic repair. | 57 eyelids, 34 patients: aponeurotic repair for involutional ptosis (landmark) |
| 1156223 | Putterman AM | 1975 | Arch Ophthalmol | Müller muscle-conjunctiva resection. Technique for treatment of blepharoptosis. | 27 of 28 eyelids satisfactory: origin of MMCR (landmark) |
| 7338007 | Loeb R | 1981 | Clin Plast Surg | Fat pad sliding and fat grafting for leveling lid depressions. | Origin of fat-sliding technique to fill the tear trough (landmark) |
| 7624408 | Hamra ST | 1995 | Plast Reconstr Surg | Arcus marginalis release and orbital fat preservation in midface rejuvenation. | 152 cases over 3 years: fat preservation instead of excision |
| 15253208 | Hamra ST | 2004 | Plast Reconstr Surg | The role of the septal reset in creating a youthful eyelid-cheek complex in facial rejuvenation. | Revision of the arcus marginalis technique to "septal reset" |
| 9787211 | Goldberg RA | 1998 | Semin Ophthalmol | Fat repositioning in lower eyelid blepharoplasty. | Describes the double-convexity deformity and fat redistribution |
| 11816085 | Goldberg RA | 1999 | Facial Plast Surg | Fat repositioning in lower blepharoplasty to maintain infraorbital rim contour. | Technique paper on maintaining rim contour with fat repositioning |
| 10697189 | Goldberg RA | 2000 | Plast Reconstr Surg | Transconjunctival orbital fat repositioning: transposition of orbital fat pedicles into a subperiosteal pocket. | 24 patients, 6-30 month follow-up: subperiosteal fat repositioning (landmark) |
| 36837432 | Kuruoglu D | 2023 | Medicina (Kaunas) | Brow and Eyelid Rejuvenation: Trends from the 100 Most Cited Articles over 30 Years. | 100 most-cited articles 1989-2020: 79% of clinical studies are level IV evidence |
| 39867419 | Rangu N | 2025 | Aesthet Surg J Open Forum | Bibliometric Analysis of the Highest Cited Cosmetic Upper Facial Plastic Surgery Articles Over 50 Years. | Top 100 articles, 50 years: surgical methods the largest study area at 30% |
| 36203097 | Gao H | 2023 | Aesthetic Plast Surg | Global Research Trends and Perspectives of Blepharoplasty: A 20-Year Bibliometric Analysis Based on Web of Science. | 1,125 publications 2002-2021: Massry GG most prolific, Hamra ST most co-cited |
| 37798496 | Hua Z | 2024 | Aesthetic Plast Surg | Letter on Global Research Trends and Perspectives of Blepharoplasty: A 20-Year Bibliometric Analysis Based on Web of Science. | Published letter responding to the 2023 bibliometric analysis |
| 37153349 | Evereklioglu C | 2023 | Indian J Plast Surg | Top 50 Most-Cited Publications on Blepharoplasty Surgery Between 2015 and 2022: From a Current Altmetric Perspective of Research Impact. | Top 50 cited 2015-2022: citations 9-37, output peaked in 2021 |
| 26994394 | Waltzman JT | 2016 | Aesthet Surg J | Who is Publishing in Facial Cosmetic Surgery? A Citation Analysis Across Specialties Over Five Decades. | Five decades of top-50 lists: ophthalmology's blepharoplasty share grew |
| 15536308 | Rohrich RJ | 2004 | Plast Reconstr Surg | Current concepts in aesthetic upper blepharoplasty. | Conservative tissue removal replaced aggressive fat excision (landmark) |
| 31802837 | Steinsapir KD | 2019 | Clin Ophthalmol | Pathology Of "Post-Upper Blepharoplasty Syndrome": Implications For Upper Eyelid Reconstruction. | 48 eyelids: levator disinsertion in septal scar from earlier aggressive fat removal |
| 3516289 | Mahaffey PJ | 1986 | Br J Plast Surg | Blindness following cosmetic blepharoplasty--a review. | Review of about 60 blindness cases, baseline safety case series (landmark) |
| 8988768 | Ramirez OM | 1996 | Ann Plast Surg | Transblepharoplasty forehead lift and upper face rejuvenation. | 14 patients: brow lift performed through the blepharoplasty incision |
| 20595828 | Codner MA | 2010 | Plast Reconstr Surg | Blepharoplasty and brow lift. | Overview of combined blepharoplasty and brow lift with supratarsal fixation |
| 32459769 | Chopan M | 2020 | Plast Reconstr Surg | Contemporary Analysis of Rhytidectomy Using the Tracking Operations and Outcomes for Plastic Surgeons Database with 13,346 Patients. | Blepharoplasty is the most common procedure added to a facelift |
| 21730839 | Allen RC | 2011 | Curr Opin Ophthalmol | The current state of ptosis repair: a comparison of internal and external approaches. | Traces the swing in preference back toward MMCR over external levator advancement |
| 38281686 | Xu J | 2024 | Clin Dermatol | Epicanthoplasty: Social and historical perspectives. | Since 1989, epicanthus surgery literature authored mainly by East Asian surgeons |
| 40913605 | Vagefi MR | 2025 | Ophthalmology | Health-Related Quality-of-Life Outcomes for Upper Blepharoplasty and Blepharoptosis Surgery: A Report by the American Academy of Ophthalmology. | AAO review of quality-of-life evidence for techniques descended from the 1975 papers |
| 33346340 | Vaca EE | 2021 | Aesthet Surg J | Current Upper Blepharoplasty and Ptosis Management Practice Patterns Among The Aesthetic Society Members. | Survey of 214 surgeons: mild to moderate ptosis still underrecognized |
| 42693598 | Whitelaw TA | 2026 | Orbit | Beyond visual field restriction: reconsidering functional assessment in upper eyelid dermatochalasis. | Argues visual field testing alone misses the burden of dermatochalasis |
Non-PubMed sources:
- The History of Cosmetic Oculoplastic Surgery — textbook-chapter excerpt naming von Graefe (1818), Sichel (1844), Miller (1907), Bourguet (1924) and Castañares (1951) with their original dates.
- The Fascinating History of Eyelid Surgery — oculoplastic-surgeon practice page, corroborates von Graefe coining "blepharoplasty" in 1818.